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In managing a patient with Graves' disease and chest pain, which treatment is most appropriate?

  1. Aspirin (ASA)

  2. Fluids restriction

  3. Amiodarone

  4. Beta blockers

The correct answer is: Beta blockers

In the management of a patient with Graves' disease presenting with chest pain, the most appropriate treatment involves the use of beta blockers. Graves' disease is an autoimmune hyperthyroid condition that can lead to symptoms such as increased heart rate and anxiety, which can both contribute to chest pain. Beta blockers are effective in controlling these symptoms by reducing heart rate and blood pressure, thereby alleviating the excess adrenergic stimulation associated with hyperthyroidism. Additionally, beta blockers provide symptomatic relief by addressing palpitations, tremors, and nervousness common in patients with hyperthyroidism. While addressing the underlying cause of Graves' disease is essential, the immediate management of symptoms such as chest pain is critical. Beta blockers can also protect the heart from potential complications related to tachycardia and high output in patients with hyperthyroidism. The other treatment options listed, such as aspirin, fluids restriction, and amiodarone, do not directly address the primary complication arising from hyperthyroidism or the symptoms presented by the patient in this scenario. Aspirin may help with pain management but does not target the underlying hyperadrenergic state caused by Graves' disease. Fluids restriction is generally not indicated unless there is a clear volume overload situation, and amiod